Author

A.-J. Twigger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:cell-cell communication· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

C. H. Scheel· 2 shared L. K. Engelbrecht· 2 shared W. T. Khaled· 2 shared A. D. Reed· 1 shared A. R. Bausch· 1 shared A. Steif· 1 shared C. J. Gabka· 1 shared D. Kunz· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

C. H. Scheel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Human Breast Cell Atlas Mapping the Homeostatic Cellular Shifts in the Adult Breast

A. D. Reed, S. Pensa, A. Steif, J. Stenning, D. Kunz, P. He, A.-J. Twigger, K. Kania, R. Barrow, I. Goulding, J. Gomm, L. Jones, J. Marioni, W. T. Khaled

This study creates a Human Breast Cell Atlas using scRNA-seq from 55 donors, identifying 41 cell subclusters and showing how factors like age and BRCA mutations affect breast homeostasis and immune cell states.

bioRxiv · Apr 21, 2023 · PreprintCancer Biology

A strategy to address dissociation-induced compositional and transcriptional bias for single-cell analysis of the human mammary gland

L. K. Engelbrecht, A.-J. Twigger, H. M. Ganz, C. J. Gabka, A. R. Bausch, H. Lickert, M. Sterr, I. Kunze, W. T. Khaled, C. H. Scheel

The paper presents a strategy to minimize dissociation-induced biases in single-cell analysis of human mammary glands by comparing different dissociation methods using single-cell RNA sequencing and flow cytometry.

bioRxiv · Feb 11, 2021 · PreprintCell Biology

Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk

A.-J. Twigger, L. K. Engelbrecht, K. Bach, I. Schultz-Pernice, S. Petricca, C. H. Scheel, W. Khaled

This study uses single-cell RNA sequencing to analyze mammary epithelial cells from human milk and non-lactating breast tissue, identifying distinct luminal cell clusters and their functional differences during lactation.

bioRxiv · Nov 6, 2020Cell Biology