Author

A. Syed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3 Microbiology· 3 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Assay:proteomics· 5 Organism:bacteria (other)· 3 Research Focus:protein folding & dynamics· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

R. Z. Sayyed· 3 shared H. A. El-Enshasy· 2 shared J. A. Tainer· 2 shared R. Sayyed· 2 shared S. Wani· 2 shared A. A. Alyousef· 1 shared A. Alqasim· 1 shared A. Boersch· 1 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

R. Z. Sayyed

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology

F. Filandr, V. Sarpe, S. Raval, D. A. Crowder, M. F. Khan, P. Douglas, S. Coales, R. Viner, A. Syed, J. A. Tainer, S. P. Lees-MIller, D. C. Schriemer

This paper develops an HX-MS2 workflow using DIA methods for automated HX data analysis, improving validation and throughput in proteomics.

Nature Communications · Mar 11, 2024Peer-reviewedBiochemistry

Development of subunit selective proteasome substrates for Schistosoma species

Z. Jiang, E. B. Da Silva, C. Liu, P. Fajtova, L. J. Liu, N. El-Sakkary, D. Skinner, A. Syed, S. C. Wang, C. J. Caffrey, A. J. O'Donoghue

The paper develops subunit-specific proteasome substrates for Schistosoma species, showing improved performance and cross-species applicability.

bioRxiv · Feb 13, 2024 · PreprintBiochemistry

Polymerase Theta Inhibition Kills Homologous Recombination Deficient Tumors

J. Zhou, C. Gelot, C. Pantelidou, A. Li, H. Yucel, R. E. Davis, A. Farkkila, B. Kochupurakkal, A. Syed, G. I. Shapiro, J. A. Tainer, B. S. Blagg, R. Ceccaldi, A. D. D'Andrea

The paper identifies Novobiocin as a POLθ inhibitor that selectively kills HR-deficient tumors, including those resistant to PARP inhibitors.

bioRxiv · May 23, 2020Cancer Biology

Tree bark scrape fungus: A potential source of laccase for application in bioremediation of non-textile dyes

H. M. Bhamare, R. Z. Sayyed, M. Marraiki, A. Elgorban, A. Syed, H. Enshasy

This study identifies Aspergillus sp. HB_RZ4 as a high-yielding laccase producer, capable of decolorizing dyes without a mediator system, making it suitable for bioremediation.

bioRxiv · Feb 20, 2020Biochemistry

Production, purification and evaluation of biodegrading potential of PHB depolymerase of Stenotrophomonas sp. RZS 7

R. Z. Sayyed, S. Wani, H. Al-Harthi, A. Syed, H. A. El-Enshasy

This study produces, purifies, and evaluates the biodegrading potential of PHB depolymerase from Stenotrophomonas sp. RZS 7, achieving 87.74% PHB degradation.

bioRxiv · Jul 10, 2019Microbiology

Thermophilic PHB depolymerase of Stenotrophomonas sp., an isolate from the plastic contaminated site is best purified on Octyl-Sepharose CL-4B

R. Sayyed, S. J. Wani, S. S. Shaikh, H. F. Al-Harthi, A. Syed, H. A. El-Enshasy

This paper reports the purification and characterization of a thermophilic PHB depolymerase from Stenotrophomonas sp. isolated from a plastic contaminated site, finding that column chromatography on Octyl-Sepharose CL-4B yields the highest purification.

bioRxiv · Apr 25, 2019 · PreprintMicrobiology

AGO1x prevents dsRNA-induced interferon signaling to promote breast cancer cell proliferation

S. Ghosh, J. Guimaraes, M. Lanzafame, A. Schmidt, A. Syed, B. Dimitriades, A. Boersch, S. Ghosh, A. Correia, J. Danner, G. Meister, L. Terracciano, S. Piscuoglio, M. Zavolan

This study identifies AGO1x, a nuclear Argonaute isoform, as a suppressor of dsRNA-induced interferon signaling that promotes breast cancer cell proliferation.

bioRxiv · Apr 10, 2019Cell Biology

Production, purification, and kinetics of the poly-β-hydroxybutyrate depolymerase from Microbacterium paraoxydans RZS6: A novel biopolymer-degrading organism isolated from a dumping yard

R. Sayyed, R. Z. SAYYED, S. Wani, A. A. Alyousef, A. Alqasim, A. Syed

This study characterizes a novel PHB depolymerase from Microbacterium paraoxydans RZS6, isolated from a plastic-contaminated site, detailing its production, purification, and kinetic properties.

bioRxiv · Feb 4, 2019Microbiology