Cancer BiologybioRxiv
Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress
L. Martinez-Ruiz, J. Florido, C. Rodriguez-Santana…·G. Escames
This study shows that intratumoral melatonin injection enhances tumor regression in head and neck cancer models by increasing mitochondrial oxidative stress and improving cisplatin efficacy.
DOI 10.1016/j.biopha.2023.115518