Author

F. Oppel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Lopez-Rodriguez· 3 shared G. Escames· 3 shared H. Sudhoff· 3 shared L. Martinez-Ruiz· 3 shared F. Brasch· 2 shared H. Pabla· 2 shared J. Florido· 2 shared L. Hose· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Lopez-Rodriguez

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4 papers

Recent·Most cited

HPV-positive head and neck squamous cell carcinoma cells lose viability during triggered myocyte lineage differentiation

S. Gendreizig, L. Martinez-Ruiz, A. Lopez-Rodriguez, H. Pabla, L. Hose, F. Brasch, T. Busche, G. Escames, H. Sudhoff, L. U. Scholtz, I. Todt, F. Oppel

This study shows HPV+ HNSCC cells lose viability during myocyte-like differentiation in vitro, with upregulated myofibril markers and potential therapeutic implications.

bioRxiv · Mar 28, 2024 · PreprintCancer Biology

Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress

L. Martinez-Ruiz, J. Florido, C. Rodriguez-Santana, A. Lopez-Rodriguez, A. Guerra-Librero, B. I. Fernandez-Gil, P. Garcia-Tarraga, J. M. Garcia-Verdugo, F. Oppel, H. Sudhoff, D. Sanchez-Porras, A. Ten-Esteve, J. Fernandez-Martinez, P. Gonzalez-Garcia, I. Rusanova, , G. Escames

This study shows that intratumoral melatonin injection enhances tumor regression in head and neck cancer models by increasing mitochondrial oxidative stress and improving cisplatin efficacy.

bioRxiv · Jul 17, 2023Cancer Biology

Inducible mucosa-like differentiation of head and neck cancer cells drives the epigenetically determined loss of cell malignancy

F. Oppel, S. Gendreizig, L. Martinez-Ruiz, J. Florido, A. Lopez-Rodriguez, H. Pabla, L. Loganathan, L. Hose, P. Kuehnel, P. Schmidt, M. Schuermann, J. M. Neumann, F. Viyof Ful, L. U. Scholtz, D. Ligum, , H. Sudhoff

This study shows that HNSCC cells can differentiate into non-malignant cells, losing their tumor-initiating potential and expressing KRT17, suggesting differentiation as a therapeutic target.

bioRxiv · Jun 30, 2023 · PreprintCancer Biology

Retinoic acid rewires the adrenergic core regulatory circuitry of neuroblastoma

M. W. Zimmerman, A. D. Durbin, S. He, F. Oppel, H. Shi, T. Tao, Z. Li, A. Berezovskaya, Y. Liu, J. Zhang, R. Young, B. J. Abraham, A. T. Look

This study shows retinoic acid reprograms enhancer landscapes in MYCN-amplified neuroblastoma cells, downregulating MYCN and inducing sympathetic differentiation.

bioRxiv · Jul 23, 2020Cancer Biology