Author

A. Thys

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. Gavard· 3 shared K. Trillet· 3 shared N. Bidere· 3 shared T. Douanne· 3 shared C. Maghe· 2 shared G. Andre-Gregoire· 2 shared K. A. Jacobs· 2 shared A. Gayraud· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

J. Gavard

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The Necroptosis Effector MLKL drives Small Extracellular Vesicle Release and Tumour Growth in Glioblastoma

G. Andre-Gregoire, T. Douanne, A. Thys, C. Maghe, K. A. Jacobs, C. Ballu, K. Trillet, I. Busnelli, V. Hyenne, J. G. GOETZ, N. Bidere, J. Gavard

This study identifies MLKL as a regulator of EV release from GSCs, showing its role in promoting tumour growth and suggesting EV targeting as a therapeutic strategy.

bioRxiv · Jan 12, 2021 · PreprintCell Biology

Serine 165 Phosphorylation of SHARPIN regulates the Activation of NF-κB

A. Thys, K. Trillet, S. Rosinska, A. Gayraud, T. Douanne, Y. Danger, C. Renaud, L. Antigny, R. Lavigne, C. Pineau, E. Com, F. Verite, J. Gavard, N. Bidere

The paper shows that phosphorylation of SHARPIN at serine 165 is required for optimal NF-κB activation, despite not affecting linear ubiquitin chain formation.

bioRxiv · Jul 2, 2020Immunology

Control of the Endo-Lysosome Homeostasis by the Paracaspase MALT1 regulates Glioma Cell Survival

K. A. Jacobs, G. Andre-Gregoire, C. Maghe, Y. Li, A. Thys, E. Harford-Wright, K. Trillet, T. Douanne, J.-S. Frenel, N. Bidere, J. Gavard

This study shows that MALT1 regulates endo-lysosome homeostasis and glioma cell survival, with MALT1 inhibition leading to lysosomal-mediated cell death.

bioRxiv · Mar 23, 2019Cell Biology