ImmunologybioRxiv
Serine 165 Phosphorylation of SHARPIN regulates the Activation of NF-κB
A. Thys, K. Trillet, S. Rosinska…·N. Bidere
The paper shows that phosphorylation of SHARPIN at serine 165 is required for optimal NF-κB activation, despite not affecting linear ubiquitin chain formation.
DOI 10.1016/j.isci.2020.101939