Author

C. Maghe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. Gavard· 4 shared K. Trillet· 4 shared N. Bidere· 4 shared K. A. Jacobs· 3 shared A. Thys· 2 shared G. Andre-Gregoire· 2 shared T. Douanne· 2 shared C. Alves Nicolau· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersCell Biology

J. Gavard

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Necrosulfonamide causes oxidation of PCM1 and impairs ciliogenesis and autophagy

C. Renaud, C. Alves Nicolau, C. Maghe, K. Trillet, J. Jardine, S. Escot, N. B. David, J. Gavard, N. Bidere

This study shows that necrosulfonamide oxidizes PCM1, disrupts ciliogenesis, and impairs autophagy, highlighting PCM1 as a redox sensor.

bioRxiv · May 5, 2023Cell Biology

The paracaspase MALT1 controls cholesterol homeostasis in glioblastoma stem-like cells through lysosome proteome shaping

C. Maghe, K. Trillet, G. A. Gregoire, M. Kerherve, L. Merlet, K. A. Jacobs, N. Bidere, J. Gavard

This study shows that MALT1 regulates cholesterol homeostasis in glioblastoma stem-like cells by shaping the lysosome proteome, leading to cell death when disrupted.

bioRxiv · Feb 27, 2023Cancer Biology

The Necroptosis Effector MLKL drives Small Extracellular Vesicle Release and Tumour Growth in Glioblastoma

G. Andre-Gregoire, T. Douanne, A. Thys, C. Maghe, K. A. Jacobs, C. Ballu, K. Trillet, I. Busnelli, V. Hyenne, J. G. GOETZ, N. Bidere, J. Gavard

This study identifies MLKL as a regulator of EV release from GSCs, showing its role in promoting tumour growth and suggesting EV targeting as a therapeutic strategy.

bioRxiv · Jan 12, 2021 · PreprintCell Biology

Control of the Endo-Lysosome Homeostasis by the Paracaspase MALT1 regulates Glioma Cell Survival

K. A. Jacobs, G. Andre-Gregoire, C. Maghe, Y. Li, A. Thys, E. Harford-Wright, K. Trillet, T. Douanne, J.-S. Frenel, N. Bidere, J. Gavard

This study shows that MALT1 regulates endo-lysosome homeostasis and glioma cell survival, with MALT1 inhibition leading to lysosomal-mediated cell death.

bioRxiv · Mar 23, 2019Cell Biology