Author

A. Volchuk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

B. E. Steinberg· 3 shared J. P. Borges· 2 shared S. Grinstein· 2 shared a. matsuzawa· 1 shared B. Kilburn· 1 shared H. Sarantis· 1 shared H. Wu· 1 shared I. Jansen· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCell Biology

B. E. Steinberg

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Author profile →

4 papers

Recent·Most cited

NINJ1 mediates plasma membrane rupture through formation of nanodisc-like rings

L. David, J. P. Borges, L. R. Hollingsworth, A. Volchuk, I. Jansen, B. E. Steinberg, H. Wu

This study identifies NINJ1's role in membrane rupture through ring formation and amphipathic helices, distinguishing it from NINJ2.

bioRxiv · Jun 1, 2023Immunology

Lipid peroxidation increases membrane tension, Piezo1 gating and cation permeability to execute ferroptosis

S. Grinstein, Y. Hirata, B. E. Steinberg, A. Volchuk, a. matsuzawa, R. Cai, S. A. Freeman

This study shows that lipid peroxidation during ferroptosis increases membrane tension, activates Piezo1 and TRP channels, and causes cation permeability, leading to cell death.

bioRxiv · Oct 31, 2022Cell Biology

Glycine targets NINJ1-mediated plasma membrane rupture to provide cytoprotection

J. P. Borges, R. S. R. Satra, A. Volchuk, M. Bugge, B. Kilburn, N. M. Goldenberg, T. H. FLO, B. E. Steinberg

This paper identifies NINJ1 as the molecular target of glycine's cytoprotective effect against plasma membrane rupture in lytic cell death.

bioRxiv · Dec 12, 2021 · PreprintCell Biology

Rab5 regulates macropinosome closure by recruitment of OCRL/Inpp5b and hydrolysis of PtdIns(4,5)P2

S. Grinstein, H. Sarantis, J. H. Brumell, A. Volchuk, M. Maxson

This study identifies Rab5's role in macropinosome closure by recruiting OCRL/Inpp5b and hydrolyzing PtdIns(4,5)P2.

bioRxiv · Jun 8, 2020 · PreprintCell Biology