Decreased fucosylation impacts epithelial integrity and increases risk for COPD.
C. Swaby, B. Yeung-Luk, S. Thapa, K. Nishida, A. Wally, B. Ghosh, A. Niederkofler, S. Luk, M. Girgis, A. Keller, C. Cortez, S. Ramaswamy, K. Wilmsen, L. Bouche, A. Dell, , V. K. Sidhaye
This study shows decreased fucosylation impairs epithelial integrity and increases COPD risk by affecting E-cadherin function and cell differentiation.
bioRxiv · Oct 31, 2023 · PreprintCell Biology