Author

A. Dell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Biochemistry· 1 Cell Biology· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 5 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

S. M. Haslam· 4 shared A. Antonopoulos· 3 shared L. Bouche· 2 shared S. Haslam· 2 shared A. Addhya· 1 shared A. Berdahl· 1 shared A. E. Friedman· 1 shared A. Filer· 1 shared

Activity by Year

2017-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersImmunology

S. M. Haslam

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Decreased fucosylation impacts epithelial integrity and increases risk for COPD.

C. Swaby, B. Yeung-Luk, S. Thapa, K. Nishida, A. Wally, B. Ghosh, A. Niederkofler, S. Luk, M. Girgis, A. Keller, C. Cortez, S. Ramaswamy, K. Wilmsen, L. Bouche, A. Dell, , V. K. Sidhaye

This study shows decreased fucosylation impairs epithelial integrity and increases COPD risk by affecting E-cadherin function and cell differentiation.

bioRxiv · Oct 31, 2023 · PreprintCell Biology

Development of a novel glycoengineering platform for the rapid production of conjugate vaccines.

S. Abouelhadid, E. Atkins, E. Kay, I. Passmore, S. J. North, B. Lehri, P. Hitchen, E. Bakke, M. Rahman, J. Bosse, Y. Li, V. S. Terra, P. Langford, A. Dell, B. W. Wren, J. Cuccui

This paper develops a novel glycoengineering platform, MAGIC, which increases glycoconjugate yield and enables vaccine development in genetically intractable bacteria.

bioRxiv · Nov 25, 2021Microbiology

Efficient Inhibition of O-glycan biosynthesis using the hexosamine analog Ac5GalNTGc

S.-S. Wang, V. del Solar, X. Yu, A. Antonopoulos, A. E. Friedman, K. Agarwal, M. Garg, S. M. Ahmed, A. Addhya, M. Nasirikenari, J. T. Lau, A. Dell, S. M. Haslam, S.-G. Sampathkumar, S. Neelamegham

This paper demonstrates that Ac5GalNTGc is a potent inhibitor of O-glycan biosynthesis, effectively reducing O-glycan elongation and modulating leukocyte functions.

bioRxiv · Dec 13, 2020Biochemistry

High mannose N-glycans on red blood cells as phagocytic ligands, mediating both sickle cell anaemia and resistance to malaria

H. Cao, A. Antonopoulos, S. Henderson, H. Wassall, J. Brewin, A. Masson, J. Shepard, G. Konieczny, B. Patel, M.-L. Williams, A. I. Davie, M. Forrester, L. Hall, B. Minter, D. Tampakis, , M. A. Vickers

bioRxiv · Nov 26, 2020 · PreprintImmunology

Regulatory T cell activation triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses

G. Wu, G. Murugesan, M. Nagala, A. McCraw, S. M. Haslam, A. Dell, P. R. Crocker

The paper investigates how Siglec-1 binding to activated regulatory T cells changes with glycosylation and identifies potential Siglec-1 counter-receptors.

bioRxiv · Jul 29, 2020 · PreprintImmunology

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in Rheumatoid Arthritis.

Y. Wang, A. Khan, A. Antonopoulos, L. Bouche, C. D. Buckley, A. Filer, K. Raza, K. Ping-Li, B. Tolusso, E. Gremese, M. Kurowska-Stolarska, S. Alivernini, A. Dell, S. M. Haslam, M. A. Pineda

This study shows that reduced α2-6 sialylation in synovial fibroblasts contributes to a pro-inflammatory phenotype in RA by altering glycosylation pathways.

bioRxiv · Mar 8, 2020Immunology

Choice of host cell line is essential for the functional glycosylation of the fragment crystallizable (Fc) region of human IgG1 inhibitors of influenza B viruses

P. A. Blundell, D. Lu, A. Dell, S. Haslam, R. Pleass

The paper compares glycosylation differences in IgG1-Fc mutants produced in HEK 293-F and CHO-K1 cells, showing cell line effects on sialylation and receptor interactions.

bioRxiv · Jul 30, 2019Immunology

Collective animal navigation and migratory culture: from theoretical models to empirical evidence

A. Berdahl, A. Kao, A. Flack, P. Westley, E. Codling, I. Couzin, A. Dell, D. Biro

The paper reviews mechanisms and empirical evidence for collective navigation in animals and explores how social learning can lead to migratory culture.

bioRxiv · Dec 7, 2017Ecology