A structural basis for prion strain diversity
S. W. Manka, A. Wenborn, J. Betts, S. Joiner, H. R. Saibil, J. Collinge, J. D. Wadsworth
This paper determines the cryo-EM structure of ME7 prion fibrils and compares it to RML fibrils, revealing structural differences that explain prion strain diversity within the same species.
bioRxiv · May 17, 2022 · PreprintBiochemistry