Author

J. Betts

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:cryo-EM· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

A. Wenborn· 2 shared H. R. Saibil· 2 shared J. Collinge· 2 shared S. Joiner· 2 shared S. W. Manka· 2 shared A. Chabowski· 1 shared A. Hengist· 1 shared A. Philp· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiochemistry

A. Wenborn

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of Th17 immunity

C.-H. Lin, C.-J. Wu, S. Cho, R. Patkar, L.-L. Lin, M.-C. Chen, E. Israelsson, J. Betts, M. Niedzielska, S. A. Patel, H. G. Duong, R. R. Gerner, C.-Y. Hsu, M. Catley, R. A. Maciewicz, , L.-F. Lu

This study identifies intestinal regulatory T cells producing IL-27 to specifically regulate Th17 immunity in the gut, revealing a novel mechanism for tissue-specific immune control.

bioRxiv · Feb 20, 2023Immunology

A structural basis for prion strain diversity

S. W. Manka, A. Wenborn, J. Betts, S. Joiner, H. R. Saibil, J. Collinge, J. D. Wadsworth

This paper determines the cryo-EM structure of ME7 prion fibrils and compares it to RML fibrils, revealing structural differences that explain prion strain diversity within the same species.

bioRxiv · May 17, 2022 · PreprintBiochemistry

2.7 A cryo-EM structure of ex vivo RML prion fibrils

S. W. Manka, W. Zhang, A. Wenborn, J. Betts, S. Joiner, H. R. Saibil, J. Collinge, J. D. F. Wadsworth

The paper presents a cryo-EM structure of prion fibrils from RML prion-infected mice, revealing structural features and conformational variations that may influence prion strain diversity and propagation.

bioRxiv · Dec 13, 2021Biochemistry

Lipid metabolism links nutrient-exercise timing to insulin sensitivity in men classified as overweight or obese.

R. Edinburgh, H. Bradley, N.-F. Adbullah, S. Robinson, O. Chrzanowski-Smith, J.-P. Walhin, S. Joanisse, K. Manolopoulos, A. Philp, A. Hengist, A. Chabowski, F. Brodsky, F. Koumanov, J. Betts, D. Thompson, , J. Gonzalez

This study shows that exercising before nutrient intake increases lipid utilization and improves insulin sensitivity in overweight or obese men over 6 weeks.

bioRxiv · Aug 21, 2019Physiology