A. Yakimovich

This study shows vaccinia virus evades xenophagy by phosphorylating and nuclear-targeting p62, preventing its role in pathogen degradation.

This study identifies ESCRT-III and VPS4 as essential for vaccinia virus packaging into multivesicular bodies, revealing an alternative pathway for virus egress.

This paper shows that the FDA-approved drug Nelfinavir inhibits lytic cell-free transmission of certain human adenoviruses but not non-lytic transmission.

The paper identifies Nelfinavir mesylate as an inhibitor of adenovirus multi-round plaque formation using an image-based high-throughput screening platform.

This study uses a zebrafish model to show that macrophages control Toxoplasma gondii infection in vivo, with type II and III strains having higher infectious burdens than type I.

The paper uses deep learning to predict lytic and nonlytic virus infections from imaging data, identifying key phenotypic differences 20 hours before lysis.

HRMAn is an open-source image analysis platform using machine learning to quantify host-pathogen interactions, demonstrating its ability to recognize and classify pathogen responses in Toxoplasma gondii and Salmonella typhimurium.

This study introduces digital holo-tomographic microscopy to observe virus-induced cytopathic effects in live cells with minimal phototoxicity and reveals virus-specific changes.