Author

A. Zask

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

A. Chavez· 2 shared B. R. Stockwell· 2 shared D. D. Ho· 2 shared H. Liu· 2 shared M. S. Nair· 2 shared S. Iketani· 2 shared S. J. Hong· 2 shared Y. Huang· 2 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. Chavez

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2 papers

Recent·Most cited

A simplified cell-based assay to identify coronavirus 3CL protease inhibitors

S. J. Resnick, S. Iketani, S. J. Hong, A. Zask, H. Liu, S. Kim, S. Melore, M. S. Nair, Y. Huang, N. E. S. Tay, T. Rovis, H. W. Yang, B. R. Stockwell, D. D. Ho, A. Chavez

This paper introduces a cell-based assay to identify coronavirus 3CL protease inhibitors without live virus, demonstrating its effectiveness through compound screening and structure-activity profiling.

bioRxiv · Aug 29, 2020 · PreprintMicrobiology

Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors

S. Iketani, F. Forouhar, H. Liu, S. J. Hong, F.-Y. Lin, M. S. Nair, A. Zask, Y. Huang, L. Xing, B. R. Stockwell, A. Chavez, D. D. Ho

The paper identifies three structurally diverse compounds as inhibitors of the SARS-CoV-2 3CL protease and provides structural insights for inhibitor design.

bioRxiv · Aug 3, 2020Microbiology