B. R. Stockwell

This study shows that suppressing ferroptosis via antioxidants or vitamin A is necessary for proper neuronal development and laminar organization in cortical organoids.

The paper identifies a metabolic vulnerability in specific glioma cell states that can be targeted with GPX4 inhibitors to induce ferroptosis.

This paper develops a multimodal mass spectrometry imaging workflow to classify liver cell types and metabolic zones at single-cell resolution in human tissue.

This paper introduces a cell-based assay to identify coronavirus 3CL protease inhibitors without live virus, demonstrating its effectiveness through compound screening and structure-activity profiling.

The paper identifies three structurally diverse compounds as inhibitors of the SARS-CoV-2 3CL protease and provides structural insights for inhibitor design.

The paper shows that targeting cystine import induces ferroptosis in pancreatic tumors, leading to tumor regression and improved survival in a mouse model.