Author

A.-K. Pfitzner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Roux· 4 shared A. Saric· 2 shared B. Baum· 2 shared B. Meadowcroft· 1 shared C. Vanhille Campos· 1 shared E. Lominadze· 1 shared f. humbert· 1 shared H. Zivkovic· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersBiophysics

A. Roux

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Modelling Membrane Reshaping by Staged Polymerization of ESCRT-III Filaments

X. Jiang, L. Harker-Kirschneck, C. Vanhille Campos, A.-K. Pfitzner, E. Lominadze, A. Roux, B. Baum, A. Saric

The paper models how ESCRT-III filaments reshape membranes through staged polymerization and depolymerization, identifying mechanical conditions for membrane deformation and scission.

bioRxiv · Oct 3, 2022Biophysics

Mechanochemical rules for shape-shifting filaments that remodel membranes

B. Meadowcroft, I. Palaia, A.-K. Pfitzner, A. Roux, B. Baum, A. Saric

The paper develops a kinetic model to study how composite filaments remodel membranes by sequentially changing composition, showing this process lowers the energetic barrier for membrane deformation.

bioRxiv · May 10, 2022Biophysics

Vps60 initiates formation of alternative membrane-bound ESCRT-III filaments

A.-K. Pfitzner, H. Zivkovic, f. humbert, A. Roux

The paper identifies Vps60 as a novel initiator of alternative membrane-bound ESCRT-III filaments that coexist with Snf7 filaments without interaction.

bioRxiv · Feb 16, 2022 · PreprintCell Biology

Vps4 triggers sequential subunit exchange in ESCRT-III polymers that drives membrane constriction and fission

A.-K. Pfitzner, V. Mercier, A. Roux

The paper shows Vps4 drives sequential ESCRT-III subunit recruitment on membranes, leading to membrane constriction and fission.

bioRxiv · Jul 29, 2019 · PreprintBiochemistry