Author

V. Mercier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Roux· 5 shared S. Matile· 3 shared C. Roffay· 2 shared G. Molinard· 2 shared J. Gruenberg· 2 shared A. Chuat· 1 shared A. Colom· 1 shared A. Goujon· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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5 shared papersBiophysics

A. Roux

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

SARS-CoV-2 shifts transcription of host gene to increase Spike acylation and boost infectivity

F. S. Mesquita, L. Abrami, L. Bracq, N. Panyain, V. Mercier, B. Kunz, A. Chuat, J. Carlevaro-Fita, D. Trono, F. G. van der Goot

This study shows SARS-CoV-2 infection alters zddhc20 transcription, producing a longer ZDHHC20 protein that enhances Spike acylation and viral infectivity.

bioRxiv · Apr 15, 2023 · PreprintCell Biology

Technical insights into fluorescence lifetime microscopy of mechanosensitive Flipper probes

C. Roffay, J. M. Garcia Arcos, P. Chapuis, J. Lopez-Andarias, F. Schneider, A. Colom, C. Tomba, I. Di Meglio, V. Dunsing, S. Matile, A. Roux, V. Mercier

The paper optimizes fluorescence lifetime imaging (FLIM) for mechanosensitive Flipper probes to measure membrane tension and long-range forces in cells, tissues, and organs.

bioRxiv · Sep 28, 2022 · PreprintBiophysics

Retromer oligomerization drives SNX-BAR coat assembly and membrane constriction

N. Gopaldass, M. G. G. De Leo, T. Courtellement, V. Mercier, C. Bissig, A. Roux, A. Mayer

This study shows retromer oligomerization drives SNX-BAR coat assembly and membrane constriction, with implications for cellular processes and disease.

bioRxiv · Jul 27, 2022Cell Biology

Quantitative coupling of cell volume and membrane tension during osmotic shocks

C. Roffay, G. Molinard, K. Kim, V. Barbarassa, M. Urbanska, V. Mercier, J. Garcia Calvo, S. Matile, J. Guck, M. Lenz, A. Roux

This study quantifies how cell volume and membrane tension change during osmotic shocks and shows they are coupled but not entirely independent.

bioRxiv · Jan 22, 2021Biophysics

Vps4 triggers sequential subunit exchange in ESCRT-III polymers that drives membrane constriction and fission

A.-K. Pfitzner, V. Mercier, A. Roux

The paper shows Vps4 drives sequential ESCRT-III subunit recruitment on membranes, leading to membrane constriction and fission.

bioRxiv · Jul 29, 2019 · PreprintBiochemistry

ENDOSOMAL MEMBRANE TENSION REGULATES ESCRT-III-DEPENDENT INTRA-LUMENAL VESICLE FORMATION

V. Mercier, J. Larios, G. Molinard, A. Goujon, S. Matile, J. Gruenberg, A. Roux

The paper shows that reduced endosomal membrane tension facilitates ESCRT-III polymerization and increases intra-lumenal vesicle formation.

bioRxiv · May 23, 2019Cell Biology

Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells

F. Vacca, S. Vossio, V. Mercier, D. Moreau, S. Johnson, J. Paz Montoya, M. Moniatte, J. Gruenberg

This study shows cyclodextrin induces endo-lysosome secretion in Niemann-Pick type C cells via MCOLN1, reducing cholesterol storage.

bioRxiv · Aug 27, 2018Cell Biology