Cancer BiologybioRxivPreprint
Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Malignant Mesothelioma
E. Sementino, Y. Kadariya, M. Cheung…·J. R. Testa
This study shows that inactivating Pak2 reduces tumor development in Nf2-deficient mice, suggesting PAK inhibition could be a therapeutic strategy for NF2-deficient cancers.
DOI 10.1101/2020.06.30.181453