M. Cheung

Novel Methylation Markers in a Prostate Cancer Cohort are Associated with Disease Development and Relapse

The paper identifies novel methylation markers in a prostate cancer cohort associated with disease development and relapse, showing their predictive power for recurrence.

Emergence of a senescent and inflammatory pulmonary CD4+ T cell population prior to lung allograft failure

The paper identifies CD4+CD57+PD1+ T cells in lung transplant recipients that predict allograft dysfunction and are associated with fibrosis in both human and mouse models.

Shared and distinct genetic features in human and canine B-cell lymphomas

This study compares genetic mutations in canine and human B-cell lymphomas, identifying shared and distinct features that may affect their biology and therapeutic development.

Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Malignant Mesothelioma

This study shows that inactivating Pak2 reduces tumor development in Nf2-deficient mice, suggesting PAK inhibition could be a therapeutic strategy for NF2-deficient cancers.

'Phase Zero' clinical study platform combining broadband Vis/near-infrared spectroscopy and electrophysiology to study human brain organoid models of neurodevelopmental disorders

The paper evaluates a clinical platform using Vis/NIR spectroscopy and electrophysiology to study E-I ratios and bioenergetics in brain organoids from schizophrenia patients.

Segmentation of Glomeruli Within Trichrome Images Using Deep Learning

This paper develops a deep learning framework to segment glomeruli in trichrome-stained kidney biopsy images, achieving high accuracy in distinguishing glomerular regions.