Author

A.-M. Lyne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Assay:scRNA-seq· 4 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

L. Perie· 4 shared E. Tubeuf· 2 shared J. Cosgrove· 2 shared S. Tenreira-Bento· 2 shared A. Ager· 1 shared A. Alfaro· 1 shared A. Dahmani· 1 shared A. Durand· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersCancer Biology

L. Perie

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CXCL8 secreted by immature granulocytes inhibits wildtype hematopoiesis in chronic myelomonocytic leukemia

P. Deschamps, M. Wacheux, A. Gosseye, M. Morabito, A. Pages, A.-M. Lyne, A. Alfaro, P. Rameau, A. Imanci, R. Chelbi, V. Marchand, A. Renneville, M. M. Patnaik, V. Lapierre, B. Badaoui, , D. Selimoglu-Buet

The paper identifies CXCL8 secreted by immature granulocytes as a factor inhibiting wildtype hematopoiesis in CMML, suggesting CXCL8 blockade could slow disease progression.

bioRxiv · Mar 8, 2024Cancer Biology

Metabolically Primed Multipotent Hematopoietic Progenitors Fuel Innate Immunity

J. Cosgrove, A.-M. Lyne, I. Rodriguez, V. Cabeli, S. Tenreira-Bento, E. Tubeuf, E. Russo, F. Tabarin, Y. Belloucif, S. Maleki-Toyserkani, S. Reed, F. Monaco, A. Ager, C. Lobry, P. Bousso, , L. Perie

The paper identifies metabolic cues that guide innate immune cell development by showing how HSPC metabolism influences myeloid differentiation and immune cell production.

bioRxiv · Jan 24, 2023 · PreprintImmunology

H3K27me3 is a determinant of chemotolerance in triple-negative breast cancer

J. Marsolier, P. Prompsy, A. Durand, A.-M. Lyne, C. Landragin, A. Trouchet, S. Tenreira-bento, A. Eisele, S. Foulon, L. Baudre, K. Grosselin, M. Bohec, S. Baulande, A. Dahmani, E. Letouze, , C. Vallot

This study identifies H3K27me3 as a key determinant of chemotolerance in triple-negative breast cancer by analyzing single-cell epigenomic and transcriptomic data.

bioRxiv · Jan 4, 2021 · PreprintCancer Biology

Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells

A. S. Eisele, J. Cosgrove, A. Magniez, E. Tubeuf, S. Tenreira Bento, C. Conrad, F. Cayrac, T. Tak, A.-M. Lyne, J. Urbanus, L. Perie

This study shows EPO directly affects murine hematopoietic multipotent progenitor cells by altering their clonal composition and inducing erythroid gene expression.

bioRxiv · Apr 20, 2020Immunology