Author

C. Lobry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

M.-C. Laiguillon· 2 shared S. Lecourt· 2 shared A. Ager· 1 shared A. Anginot· 1 shared A. Bonaud· 1 shared A. Petit· 1 shared A. Pierson· 1 shared A. Puissant· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

M.-C. Laiguillon

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CXCR4 signaling strength regulates hematopoietic multipotent progenitor fate through extrinsic and intrinsic mechanisms

V. Rondeau, M. Kalogeraki, L. Roland, Z. A. Nader, V. Gourhand, A. Bonaud, J. Lemos, M. Khamyath, C. Moulin, B. Schell, M. Delord, G. Bidaut, S. Lecourt, C. Freitas, A. Anginot, , K. Balabanian

This study shows that CXCR4 signaling strength influences hematopoietic multipotent progenitor fate through both extrinsic and intrinsic mechanisms, with implications for myeloid skewing in WHIM Syndrome.

bioRxiv · May 31, 2023 · PreprintCell Biology

Metabolically Primed Multipotent Hematopoietic Progenitors Fuel Innate Immunity

J. Cosgrove, A.-M. Lyne, I. Rodriguez, V. Cabeli, S. Tenreira-Bento, E. Tubeuf, E. Russo, F. Tabarin, Y. Belloucif, S. Maleki-Toyserkani, S. Reed, F. Monaco, A. Ager, C. Lobry, P. Bousso, , L. Perie

The paper identifies metabolic cues that guide innate immune cell development by showing how HSPC metabolism influences myeloid differentiation and immune cell production.

bioRxiv · Jan 24, 2023 · PreprintImmunology

Screening of clustered regulatory elements reveals functional cooperating dependencies in Leukemia.

S. Benbarche, C. K. Lopez, E. Salataj, C. Thirant, M.-C. Laiguillon, Z. Aid, S. Lecourt, M. Antonini, B. Pardieu, A. Petit, A. Puissant, J. Chaumeil, T. Mercher, C. Lobry

The paper identifies co-regulated genes in leukemia using CRISPRi screening of super-enhancer regions, showing that combined inhibition of KIT and PDGFRA synergizes to impair leukemia cell growth.

bioRxiv · Jun 24, 2019 · PreprintCancer Biology

Splicing inhibition enhances the antitumor immune response through increased tumor antigen presentation and altered MHC-I immunopeptidome

A. Pierson, R. Darrigrand, M. Rouillon, M. Boulpicante, Z. D. Renko, C. Garcia, M. Ghosh, M.-C. Laiguillon, C. Lobry, M. Alami, S. Apcher

This study shows that splicing inhibition with IP2 enhances antitumor immunity by increasing antigen presentation and altering MHC-I immunopeptidomes.

bioRxiv · Jan 6, 2019 · PreprintImmunology