Cancer BiologybioRxivPreprint
Avoidance of pyroptosis accounts for the relatively high metastatic potential observed in early hybrid EMT states
Aakanksha Verma, Alessandro Genna, Yaron Vinik…·Yosef Yarden
The paper identifies Arrdc4's role in suppressing pyroptosis in biphenotypic EMT cells, linking its downregulation to increased metastatic potential and poor prognosis in breast cancer.