Molecular BiologybioRxivPreprint
Structure-optimized sgRNA selection with PlatinumCRISPr for efficient Cas9 generation of knock-outs
Irmgard U. Haussmann, Thomas C. Dix, David W. J. McQuarrie…·Matthias Soller
The paper develops PlatinumCRISPr, a tool for selecting efficient sgRNAs for CRISPR-Cas9 genome editing, identifies design constraints, and reports unintended DNA insertions from deletions.
6 citations