David W. J. McQuarrie

The paper investigates rapid promoter evolution and expression divergence of male accessory gland genes in closely related Drosophila species, showing cis-regulatory changes drive expression differences.

The paper identifies DOA/CLK2 as a kinase that phosphorylates Fl(2)d/WTAP to enhance m6A methyltransferase complex activity, crucial for dosage compensation and splicing regulation.

The paper shows that promoters of germline-specific piRNA factors evolve rapidly in Drosophila and other insects, potentially driving gene expression divergence.

This study shows that reducing Dscam expression enhances memory retention in honey bees and alters its alternative splicing during memory consolidation.

The paper develops PlatinumCRISPr, a tool for selecting efficient sgRNAs for CRISPR-Cas9 genome editing, identifies design constraints, and reports unintended DNA insertions from deletions.