PathologybioRxivPreprint
Inhibition of methylthioadenosine phosphorylase provides protection from experimental acute kidney injury
Afaf Saliba, Yidong Chen, Jonathan W. Nelson…·Kumar Sharma
This study shows that inhibiting MTAP reduces kidney injury markers and improves renal histology in AKI mouse models and links MTAP expression to kidney injury in human single-cell RNA sequencing data.
DOI 10.1101/2025.02.19.639065