MicrobiologyInfection and ImmunityPeer-reviewed
Understanding the Role of Pyruvate Dehydrogenase in Listeria monocytogenes Virulence
Matthew J. Freeman, Noah J. Eral, Abigail M. Debrine…·John‐Demian Sauer
This study identifies PDH complex defects in L. monocytogenes as critical for intracellular survival, showing that PDH mutants fail to utilize PTS-dependent carbon sources, leading to reduced virulence.
DOI 10.1128/iai.00505-25