Cell BiologybioRxivPreprint
TLR4-dependent signaling drives extracellular catabolism of low-density lipoprotein aggregates
Rajesh K. Singh, Abigail S. Haka, Arky Asmal…·Frederick R. Maxfield
This study shows TLR4 signaling promotes extracellular catabolism of LDL aggregates and lipid accumulation in macrophages through lysosomal synapse formation.
DOI 10.1101/610162