In vivo cellular localisation and nanoscale organisation of NLRP3 inflammasomes
Christopher Hoyle, Benjamin Llewellyn, Helen Parker, Katie N. Murray, Andrew D. Greenhalgh, Jonathan D. Worboys, Rodrigo Diaz Pino, Julia Ogden, Adam Johnson, Antony D. Adamson, Kevin N. Couper, Catherine B. Lawrence, Gloria López‐Castejón, Martin Lowe, David Brough, Jack Green
This study uses reporter mice to visualise NLRP3 inflammasomes in vivo, revealing their localisation, organisation, and cellular sources.
bioRxiv · Aug 12, 2026 · PreprintImmunology