Richard M. Walsh

The paper structures ZmaM, a type II peptidase-ABC transporter in B. cereus, showing it activates and exports zwittermicin A by coordinating peptidase and transporter modules.

The paper reports a cryo-EM structure of the S2 fragment of SARS-CoV-2 after S2 cleavage, showing it represents a late fusion intermediate, and shows that S2 cleavage accelerates membrane fusion.

The paper determines the cryo-EM structure of immature, small VLPs of dengue virus type 2, revealing octahedral symmetry and prM-E heterodimer clustering, with implications for vaccine design.

This study determines the pre-activation structure of the herpesvirus gH/gL complex and identifies an allosteric mechanism for transmitting fusion signals from gD to gB.

The paper uses cryo-EM to visualize the assembly of the human 20S proteasome, revealing how chaperones and propeptides guide subunit incorporation and proteasome activation.

The paper determines the structure of BmGr9, an insect gustatory receptor, and compares it to olfactory receptors to understand ligand specificity.