BiochemistrybioRxiv
Using energy to go downhill - a genoprotective role for ATPase activity in DNA topoisomerase II
Afif F Bandak, Tim R Blower, Karin C Nitiss…·James M Berger
This study shows that ATPase activity in type II topoisomerases prevents excessive DNA damage by regulating strand passage and cleavage.
DOI 10.1093/nar/gkad1157