BiophysicsbioRxiv
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation
Karin E. J. Rödström, Alexander Cloake, Janina Sörmann…·Stephen J. Tucker
The paper identifies nanobodies that selectively modulate TREK-2 channel activity and reveals their binding mechanisms through structural analysis.
DOI 10.1038/s41467-024-48536-2