Cancer BiologybioRxivPreprint
Sialylated CD43 is a glyco-immune checkpoint for macrophage phagocytosis
Jooho Chung, Mounica Vallurupalli, Sarah Noel…·Robert T. Manguso
The paper identifies CD43 as a glyco-immune checkpoint that inhibits human macrophage phagocytosis, showing that O-linked glycosylation and sialylation pathways regulate this process in AML.