Cancer BiologybioRxivPreprint
Radiotherapy drives lung metastasis in PDAC via a RhoGTPasesignaling shift towards MRCK-dependency
Kathy McLay, Mathias Tesson, Louise R. Dutton…·JL Birch
This study shows that radiotherapy promotes lung metastasis in PDAC by increasing MRCK activity, which can be inhibited by BDP9066.
DOI 10.1101/2025.09.09.673965