Cancer BiologybioRxiv
Leukemia-mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness
Aishwarya Pawar, Patrick Somers, Aleena Alex…·Vikram R. Paralkar
This study identifies PHF6 and PHIP as a chromatin complex that represses AML stemness, showing their functional relationship and the impact of their mutations.