Author
University of PennsylvaniaORCID 0000-0002-5932-9236Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Aishwarya Pawar, Patrick Somers, Aleena Alex…·Vikram R. Paralkar
This study identifies PHF6 and PHIP as a chromatin complex that represses AML stemness, showing their functional relationship and the impact of their mutations.
Sapana S. Jalnapurkar, Aishwarya Pawar, Subin S. George…·Vikram R. Paralkar
This study shows that PHF6 loss increases AML aggressiveness by enhancing leukemia stem cell self-renewal through context-specific transcriptional changes.
Charles Antony A, Subin S. George, Justin Blum…·Vikram R. Paralkar
The paper identifies cell-type-specific transcription factors that bind rDNA and regulate rRNA transcription, showing CEBPA's role in promoting Pol I occupancy and rRNA synthesis in myeloid progenitors.