Author

Alejandro García López

University Medical Center Groningen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Bert van de KooijiD· 1 shared Dan Ruan· 1 shared Femke J. BakkeriD· 1 shared Frank N. MoliD· 1 shared H. Rudolf de BoeriD· 1 shared Harry M. WarneriD· 1 shared Lauren de HaaniD· 1 shared Marcel A.T.M. van VugtiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Bert van de KooijORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintApr 3, 2025

CIP2A is required for mitotic recruitment of the SLX1/XPF/MUS81 tri-nuclease complex to replication stress-induced DNA lesions to maintain genome integrity

Lauren de Haan, Sietse J. Dijt, Alejandro García López…·Marcel A.T.M. van Vugt

This study shows that CIP2A-TOPBP1 recruits the SMX tri-nuclease complex to resolve mitotic DNA lesions, ensuring genome integrity and survival of BRCA2-deficient cells.

4 citations

humanDNA methylation

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