Author

Aleksandra Dabrowska

Imperial College London

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Cancer Biology· 1

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Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

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Justin StebbingiD· 1 shared Leandro CastellanoiD· 1 shared Mark E. RobinsoniD· 1 shared Niklas FeldhahniD· 1 shared Silvia OttavianiiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperCancer Biology

Justin StebbingORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMay 30, 2025

Single-cell transcriptomics uncovers that cell-to-cell communication controls p53 activation

Leandro Castellano, Mark E. Robinson, Aleksandra Dabrowska…·Justin Stebbing

The paper uses single-cell RNA sequencing to show that cell-to-cell communication enhances p53 activation in response to chemotherapy, revealing a role for paracrine signaling in treatment response.

DOI 10.1101/2025.05.30.657016

humanscRNA-seq

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