Resolving heterogeneity of targeted lipid nanoparticles through solution-based biophysical analyses
Hannah C. Geisler, Hannah C. Safford, Ajay S. Thatte…·Michael J. Mitchell
This study resolves heterogeneity in targeted lipid nanoparticles (tLNPs) using biophysical methods, showing that subpopulation structure, not bulk properties, determines targeted RNA delivery.