Developmental BiologyOpen BiologyPeer-reviewed
Mild activation of the mitochondrial unfolded protein response increases lifespan without increasing resistance to stress
Alexa Di Pede, Bokang Ko, Abdelrahman AlOkda…·Jeremy M. Van Raamsdonk
This study shows that mild activation of the mitochondrial unfolded protein response (mitoUPR) through ATFS-1 can increase lifespan without enhancing stress resistance in worms.
10 citations