Evolutionary BiologyPLOS GeneticsPeer-reviewed
Age-related and heteroplasmy-related variation in human mtDNA copy number
Manja Wachsmuth, Alexander Huebner, Mingkun Li…·Mark Stoneking
This study examines mtDNA copy number variation across tissues and age, finding age-related decreases in skeletal muscle and increases in liver, with heteroplasmic sites linked to mtCN changes in muscle.
DOI 10.1371/journal.pgen.1005939