Mingkun Li

A fuzzy sequencer improves information efficiency and accuracy in DNA resequencing applications.

The paper compares SARS-CoV-2 variants from China and other countries, finding that Chinese variants have more dispersed RBD mutations with higher ACE2 binding and less immune evasion potential due to a distinct immune background.

The paper compares antibody responses from individuals with XBB reinfection and those vaccinated with WSK-V102C, showing the vaccine induces stronger neutralization against SARS-CoV-2 variants including JN.1 and BA.2.87.1.

This study evaluates the neutralization efficacy of a tetravalent vaccine booster against emerging SARS-CoV-2 variants, finding it induces higher neutralizing titers than breakthrough infection.

This study analyzes the genomic features of the SARS-CoV-2 Omicron variant, identifying its high mutation rate, spike protein alterations, and distinct evolutionary patterns.

This study uses hybrid capture sequencing to recover SARS-CoV-2 genomes from fecal samples, revealing dynamic intra-host variant changes and viral viability in the gastrointestinal tract during convalescence.

The paper examines mtDNA heteroplasmy sharing between human liver lobes, finding higher sharing in the control region and suggesting selection influences this pattern.

This study examines mtDNA copy number variation across tissues and age, finding age-related decreases in skeletal muscle and increases in liver, with heteroplasmic sites linked to mtCN changes in muscle.

The paper analyzes Y chromosome and mtDNA sequences from 623 males to study human paternal and maternal demographic histories, finding larger genetic differences for Y chromosomes, small ancestral population sizes, and a growing female-to-male effective population size ratio.