BiochemistryProtein SciencePeer-reviewed
Engineered Antigen-Binding Fragments for Enhanced Crystallisation of Antibody:Antigen Complexes
Heather A. Bruce, Alexander U. Singer, Ekaterina V. Filippova…·Sachdev S. Sidhu
This study identifies surface substitutions that enhance the crystallisation of Fab:antigen complexes by combining surface entropy reduction with phage-display technology and previously reported substitutions.
7 citations