Author

Ekaterina V. Filippova

University of ChicagoORCID 0000-0001-6382-4929Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Organism:human· 1

Frequent Co-Authors

Anthony A. KossiakoffiD· 2 shared Alexander U. Singer· 1 shared Daniel Y.L. MaoiD· 1 shared Elizabeth RadleyiD· 1 shared Els PardoniD· 1 shared Frank SicheriiD· 1 shared Heather A. Bruce· 1 shared Igor V. KurinoviD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Anthony A. KossiakoffORCID

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2 papers

Recent·Most cited

BiochemistryProtein SciencePeer-reviewedNov 10, 2023

Engineered Antigen-Binding Fragments for Enhanced Crystallisation of Antibody:Antigen Complexes

Heather A. Bruce, Alexander U. Singer, Ekaterina V. Filippova…·Sachdev S. Sidhu

This study identifies surface substitutions that enhance the crystallisation of Fab:antigen complexes by combining surface entropy reduction with phage-display technology and previously reported substitutions.

7 citations

humanprotein structure

𝕏 PostBluesky

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedNov 15, 2021

Development of a universal nanobody-binding Fab module for fiducial-assisted cryo- EM studies of membrane proteins

Joël S. Bloch, Somnath Mukherjee, Julia Kowal…·Kaspar P. Locher

The paper develops a synthetic Fab module (NabFab) that binds nanobodies with high affinity, enabling high-resolution cryo-EM studies of membrane proteins.

114 citationstop 3%

protein structureexperimental assay

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