Cancer BiologybioRxivPreprint
Grubraw, a chemogenetic mitochondrial activator, reveals new mechanisms underlying the Warburg effect
Ekaterina S. Potekhina, Dina Y. Bass, Alexander V. Ivanenko…·Vsevolod Vadimovich Belousov
The paper introduces Grubraw, a chemogenetic tool that activates mitochondrial respiration in Warburg-type cancer cells, revealing that mitochondrial pyruvate export and reduced proliferation occur.
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