Molecular BiologyNAR CancerPeer-reviewed
Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma
Christina M. Fitzsimmons, Mariana D. Mandler, Judith C. Lunger…·Pedro J. Batista
This study investigates how fumarate accumulation affects RNA methylation by targeting specific 2OGDD enzymes in HLRCC cell lines, revealing differential impacts on m6A, m1A, and f5C demethylases.
18 citations