Christina M. Fitzsimmons

The paper identifies tRNA modifications in P. aeruginosa by comparing them to E. coli, revealing conserved and unique modification sites.

This study investigates how fumarate accumulation affects RNA methylation by targeting specific 2OGDD enzymes in HLRCC cell lines, revealing differential impacts on m6A, m1A, and f5C demethylases.

This study shows that TMT1A's ability to methylate thiol-based HDAC inhibitors is conserved across species, suggesting its functional relevance in animal models.

The paper benchmarks eight tools for identifying and quantifying alternative polyadenylation sites from RNA-seq data using real, synthetic, and 3'-end sequencing data.

Inserting theophylline aptamers into the sgRNA yields ligand-activated and ligand-deactivated guides that tune CRISPRi in E. coli over 11x to 13x dynamic ranges, enabling two-ligand multiplexing.