Precision RNAi using synthetic shRNAmir target sites
Thomas Hoffmann, Alexandra Hörmann, Maja Corcokovic…·Ralph A. Neumüller
This paper introduces ARTi, a method using synthetic shRNAs to achieve precise and controllable RNAi for gene suppression.
Author
Boehringer Ingelheim (Austria)
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Thomas Hoffmann, Alexandra Hörmann, Maja Corcokovic…·Ralph A. Neumüller
This paper introduces ARTi, a method using synthetic shRNAs to achieve precise and controllable RNAi for gene suppression.
Teresa Krammer, Hannah T. Stuart, Elena Gromberg…·Elly Margaret Tanaka
The paper shows how floorplate organiser forms autonomously in neural tube organoids through BMP-mediated cluster competition and FOXA2 dynamics.
Anna Köferle, Andreas Schlattl, Alexandra Hörmann…·Ralph A. Neumüller
The paper identifies novel paralog gene dependencies in cancer, including sex chromosome-encoded gene pairs, suggesting therapeutic strategies for tumors with Y-chromosome loss.