ImmunologybioRxiv
Parasite-Induced IFN-g Regulates Host Defense via CD115 and mTOR-Dependent Mechanism of Tissue-Resident Macrophage Death
Andrew T. Martin, Shilpi Giri, Alexandra Safronova…·Felix Yarovinsky
This study shows that IFN-gamma induces CD115 and mTOR-dependent death of tissue-resident macrophages, enhancing host resistance to Toxoplasma gondii.
DOI 10.1371/journal.ppat.1011502