Author
University of North Carolina at Chapel Hill
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Eric L. Garcia, Rebecca E. Steiner, Amanda C. Raimer, Laura E. Herring, A. Gregory Matera, Ashlyn M. Spring
This study identifies hyperactivation of innate immune signaling as a consequence of SMN depletion in Drosophila SMA models, revealing a conserved regulatory role of the SMN complex.
BMC Biology · Apr 25, 2024Peer-reviewedGenetics
Amanda C. Raimer, Suhana S. Singh, Maina R. Edula, Tamara Paris‐Davila, Vasudha Vandadi, Ashlyn M. Spring, A. Gregory Matera
This paper shows that temperature-sensitive SMA-causing mutations in Drosophila SMN lead to SMN instability, locomotor defects, and premature death, highlighting SMN's role in development.
Disease Models & Mechanisms · Jan 1, 2020Peer-reviewedGenetics
Ashlyn M. Spring, Amanda C. Raimer, Christine D. Hamilton, Michela J. Schillinger, A. Gregory Matera
This study models spinal muscular atrophy in Drosophila using patient-derived missense mutations, showing similar phenotypes to human SMA across multiple adult neuromuscular metrics.
Frontiers in Molecular Neuroscience · May 16, 2019Peer-reviewedNeuroscience
A. Gregory Matera, Amanda C. Raimer, Casey A. Schmidt, Jo A. Kelly, Gaith N. Droby, David Baillat, Sara ten Have, Angus I. Lamond, Eric J. Wagner, Kelsey M. Gray
The paper identifies CG2941 as a Gemin4 ortholog in Drosophila melanogaster and shows its essential role in organismal viability.
G3 Genes Genomes Genetics · Dec 18, 2018Peer-reviewedGenetics