Gaith N. Droby

This paper identifies CD73 as a regulator that limits oncogenic activity of mutant β-catenin in endometrial carcinomas, showing that its loss increases transcriptional activity and tumor progression.

This study shows Rad18 suppresses 4NQO-induced oral carcinogenesis but not KrasG12D-driven lung tumors, highlighting context-specific tumor-suppressive roles.

This study identifies RNF25's role in protecting DNA replication forks from degradation, independent of its ubiquitin signaling functions.

This study identifies TRIP13 as a key factor protecting KRAS-mutant pancreatic cancer cells from DNA replication stress and therapy-induced damage.

This study identifies MAPK14/p38α as critical for HGEC spheroid growth, shaping its transcriptomic, proteomic, and metabolomic landscapes and promoting tumorigenic properties.

This study identifies RAD18's role in TMZ resistance and hypermutation in GBM by linking it to TLS and MMR pathways through CRISPR screening and mutation analysis.

The paper identifies CG2941 as a Gemin4 ortholog in Drosophila melanogaster and shows its essential role in organismal viability.